NEW YORK -- Stocks that traded heavily or had substantial price changes Wednesday:

       Canadian National Railway Co., up $6.50 to $130.79.

       The railroad operator beat Wall Street's third-quarter profit and revenue forecasts.

       Anthem Inc., up $30.30 to $424.05.

       The health insurer's third-quarter profit beat analysts' forecasts.

       Brinker International Inc., down $4.74 to $44.21.

       The owner of the Chili’s Grill & Bar and Maggiano’s Little Italy restaurant chains warned investors higher commodity and labor costs would hurt profits.

       Lithia Motors Inc., up $3.30 to $342.01.

       The auto dealership chain handily beat Wall Street's third-quarter profit and revenue forecasts.

       WD-40 Co., down $20.09 to $209.20.

       The maker of lubricants and degreasers' fiscal fourth-quarter profit fell far short of Wall Street forecasts.

       Baker Hughes Co., down $1.52 to $25.35.

       The oilfield services company reported weak third-quarter financial results as it faces supply chain problems and higher costs.

       Abbott Laboratories, up $3.97 to $123.31.

       The maker of infant formula and medical devices handily beat analysts’ third-quarter profit forecasts.

       Knight-Swift Transportation Holdings Inc., up $3.57 to $54.32.

       The trucking company reported encouraging third-quarter financial results on strong shipping demand.