Stocks that traded heavily or had substantial price changes Wednesday:

       CVS Health Corp., down $6.04 to $104.79.

       The drugstore chain and pharmacy benefits manager gave investors a discouraging earnings forecast.

       Chipotle Mexican Grill Inc., up $148.39 to $1,608.74.

       The Mexican food chain's fourth-quarter financial results beat analysts' forecasts.

       Paycom Software Inc., up $29.93 to $364.94.

       The maker of human-resources and payroll software gave investors a strong revenue forecast.

       Yum Brands Inc., up $2.73 to $127.70.

       The parent company of KFC, Taco Bell and Pizza Hut beat Wall Street's fourth-quarter revenue forecasts.

       Mandiant Inc., up $1.27 to $19.02.

       Microsoft is reportedly considering buying the computer security software company.

       XPO Logistics Inc., up $5.34 to $69.68.

       The freight transportation company reported strong fourth-quarter earnings and revenue.

       NCR Corp., up $5.48 to $43.78.

       The maker of ATMs reported encouraging fourth-quarter financial results and announced a strategic review of its operations.

       New Relic Inc., down $30.95 to $78.23.

       The cloud-based software analytics company gave investors a disappointing earnings forecast.