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In a fit of pique after sustaining a major geopolitical blow, Iran’s supreme leader wheeled out the usual suspects. “The main plotter, the main planner, the main agent, the main command room is in the United States and in the Zionist regime,” Ayatollah Ali Khamenei said Wednesday to a crowd in Tehran, blaming Israel and the Biden administration for orchestrating the uprising that recently toppled Syrian President Bashar al-Assad, a staunch Iranian ally. Both Iran and Assad’s other enabler, Russia, are stewing in humiliation as the dramatic changing of the guard in Damascus unfolds.