NEW YORK -- Stocks that traded heavily or had substantial price changes Monday:

       Arena Pharmaceuticals Inc., up $40.14 to $90.08.

       Pfizer is buying the drug developer for $6.7 billion.

       Harley-Davidson Inc., up $1.73 to $38.54.

       The motorcycle maker will take its electric motorcycle division public through a blank-check company.

       Bristol-Myers Squibb Co., up $2.69 to $59.05.

       The drug developer raised its quarterly dividend and added $15 billion to its buyback program.

       IGM Biosciences Inc., down $20.59 to $29.25.

       Investors were disappointed with the biotechnology company's update on a potential cancer treatment.

       Capital One Financial Corp., down $4.37 to $146.04.

       Bond yields fell and weighed down banks, which rely on higher bond yields to charge more lucrative interest on loans.

       Carnival Corp., down 94 cents to $18.34.

       Cruise lines and travel-related stocks fell over concerns about the newest coronavirus variant's potential impact on the industry.

       Eli Lilly and Co., up $4.39 to $248.53.

       The drug developer is collaborating with Foghorn Therapeutics for potential cancer treatments.

       Baxter International Inc., up $2.34 to $83.20.

       The medical technology company completed its buyout of Hillrom.